5 Best St. Louis Missouri Casinos (April 2024)

St. Louis is the second biggest city in Missouri and is located just within the state border. Overlooking the Mississippi River, the city is rife with history. Baseball fans will know St. Louis for being the home of the St. Louis Cardinals. The Cardinals are one of the oldest franchises in the MLB and are second only to the NY Yankees in titles. Then, there are the St. Louis Blues, who play in the NHL and won the Stanley Cup in 2019. The most recent addition to the sports scene in St. Louis was the St. Louis City SC, in the MLS. The soccer team was launched in 2019 and began playing in the MLS in the 2023 season.

St. Louis also has plenty of gaming facilities, where you can play exciting casino games. These casinos are regulated by the Missouri Gaming Association, and completely safe to play at. So next time you are in St. Louis and have a little spare time to kill, you can check out one of these casinos.

1. Horseshoe St. Louis Casino and Hotel

This casino hotel used to be called Lumiere Place before it was rebranded as Horseshoe St. Louis in 2022. It is operated by Caesars Entertainment, it is located in downtown St. Louis. The casino hotel has 500 rooms and won the Rerader's Choice award for Best Casino in 2013. It has 4 restaurants: Cinder House, Morton's The Steakhouse, Riverfront Grill and The Slice Pizzeria and Pasta. You can also go shopping in the Horseshoe St. Louis or check into the spa for some excellent wellness treatments.

The Horseshoe St. Louis has 75,000 square feet of gaming space, featuring more than 1,100 slots and 33 gaming tables. As it is a part of the Caesars brand, you can sign up for the Caesars loyalty program at Horseshoe can collect valuable tier credits. If you are already a part of the program, you will know that there are loads of benefits, including massive giveaways and promotions. The latter can be used across the gaming facilities at the Horseshoe. To top it off, there are also 10 tables in a dedicated poker room. The Horseshoe St. Louis has hosted WSOP Poker tournaments, and there are loads of cash games to try out. Whether Three Card Poker or Ultimate Texas Hold'em are your thing, you can find loads of opportunities to bring your A-game at Horseshoe. There are also high limit tables where you can play with bigger stakes for mammoth top prizes.

Best For: Poker Enthusiasts

2. Hollywood Casino and Hotel St. Louis

Hollywood Casino St. Louis is a little further out from the city centre. It is located in Maryland Heights, a suburb of Missouri. The casino is run by Penn Entertainment, which operates over 40 casinos across the country. The complex has a hotel, casino, dining options and entertainment venues. The Hollywood Casino Amphitheatre is an indoor/outdoor music venue that hosts all sorts of music concerts. It also has an on-site 99 Hops House, where you can get some special craft beers. The St. Louis Music Park is a 4,500-seater multipurpose venue, which exudes festival vibes. If you stay at one of the 502 rooms at Hollywood Casino, you can get some great discounts on concerts at either venue. There is a variety of dining options at Hollywood Casino, such as Phat Tai, Charlie Gitto's Celebrity Grill, and more.

Heading into the casino, there are over 1,600 slots spread out across 120,000 square feet of gaming space. These gaming machines offer the hottest games that you can find, including Buffalo Chief, Lockit Link, Dragon Unleashed, Triple Blazing 7's and many more. Hollywood Casino also houses a tonne of Asian games, such as ten variants of Baccarat, which you can try out while you eat Asian food in Phat Tai. You can sit at any of the 46 gaming tables to play a round of Blackjack, Craps or Roulette. If you want to splash out, you can hit the high limit room, where there is more Blackjack. Poker is also a big thing at Hollywood Casino. Omaha High/Low, No Limit Hold'em and Limit Hold'em are offered, and there are 20 tables to pick from. Look out for Bad Beat Jackpot and Special Hand Jackpot cash games.

Best For: Gamers who like Asian Games

3. Ameristar Casino Resort Spa

Ameristar Casino Resort Spa is a riverboat casino on the Missouri River, up in the northwestern suburb of St. Louis, St. Charles. The casino is owned and run by Boyd Gaming, and was opened in 1994. Every year, the casino draws in over 5.5 million visitors, who come for the excellent accomodation, dining and gaming facilities. The hotel has 400 full service luxury suites, with a pool, seven restaurants, 12 bars and an entertainment venue. Ameristar also has a Spa, with wellness treatments, pools, and a boutique for beauty treatments. You can eat all sorts of excellent food at Ameristar, from local Oysters and Cajun/Creole food to exotic Asian dishes. The Pearl's Oyster Bar, King Cat Club, Fifth Street Deli, Asia and Amerisports Bar & Grill have some exceptional menus. The Amerisports Bar & Grill also has TVs where you can watch sports games as you tuck into some classic American meals.

Ameristar houses a 130,000 square foot casino, with over 1,700 state-of-the-art slots. You can spin the reels for as little as 1 cent or play for $100 per spin on the games. The casino also has a high limit salon, where there are 16 progressive slots that have top prizes starting from $20,000 and increasing every second. Craps is one of the most popular table games at Ameristar, as it has a 20x payout. Blackjack buffs will revel in the $10,000 limits on Blackjack games, so they can really swing for the fences. Another great feature is the Baccarat Pit, where you can immerse yourself in the games and go for the top prizes.

Best For: Craps Players

4. River City Casino Hotel

The River City Casino is in Lemay, Great St. Louis. Just like the Hollywood Casino and Hotel, this casino is operated by Penn Entertainment. The theme of the hotel casino is the 1904 World's Fair, which was held in St. Louis, Missouri. The complex is truly a blast from the past, with beautiful neoclassic buildings and decor, which all light up during the night. The establishment has a hotel, five diners and an entertainment venue called Judy's Velvet Lounge. The venue has a roaring 20's theme, with grandiose art deco decorations and silky smooth cocktails. Foodies can delight in the menus at Burger Brothers, Cibare Italian Kitchen, The Beerhouse, Asia Noodles and the 1904 Steak House. The latter is the pick of the bunch, with 120 wines from around the world, Oysters Rockefeller and the tastiest prime cuts.

River City has a 90,000 square foot casino, packed with 1,700 slots, over 40 tables and a special room dedicated to Baccarat. If that is not enough, there is a high limit room on the casino floor, where you can experience first class service. The room has Blackjack games and dozens of slots, and eye-catching top prizes. Slots players have a tonne of games to explore, and they can go for the high limit stakes or play for as little as 1 cent. There are loads of high paying video slots with a plethora of interactive bonus rounds and animations, The games take on a life of their own through the cutting edge machines.

Best For: Slots and High-Tech Gaming Machines

5. DraftKings at Casino Queen (Illinois)

Casino Queen is in East St. Louis, Illinois, just across the Mississippi River. Though it is not in Missouri, it is a lot closer than casinos such as Hollywood or Ameristar to downtown St. Louis. The casino is operated by The Queen Casino & Entertainment and has a deal with the popular sports betting provider, DraftKings. It is a riverboat casino, with a hotel, four restaurants, a bar and a cafe. The 3 Woks Noodle Bar is a casual diner with a huge offering of Asian food. If burgers and sandwiches are more your thing, you can check into the Bridgeway or That Chikn' Place. For sports fans, it does not get better than the DraftKings at Casino Queen Sportsbook. You can order some delicious burgers or finger food as you pull up a chair and watch the games. The sportsbook has 38 betting kiosks and 5 betting windows, so you can get in on the betting action too.

The casino may be small, only measuring 38,000 square feet, but it packs a wide variety of games. There are 980 slots to try out, including highly demanded games such as Dragon Link, Mighty Cash, Rising Fortunes and Spin It Grand. The casino also provides a wide range of table games, that can be enjoyed by beginners and pros alike. You can try your hand at Blackjack, Craps, Roulette, or poker games such as Mississippi Stud, Ultimate Texas Hold'em and Three Card Poker.

Best For: Sports Bettors at the DraftKings Sportsbook

Conclusion

Though one of the sportsbooks on our list is not technically in the state of Missouri, it is still within the greater area of St. Louis. All the casinos have their own special features and unique atmosphere. They also have great dining options and hotels where you can book a stay in the height of luxury. At the DraftKings sportsbook, you will also have the chance to bet on the St. Louis MLB, MLS and NHL franchises too.